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MAPK
Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index T
Tradipitant
(Catalog# : 011810, Cas# :
622370-35-8
)
Tradipitant is the 2nd generation neurokinin-1 receptor antagonist, which showed acti
TGN 255
(Catalog# : 011114, Cas# :
871576-03-3
)
Coming soon!
TAK-733
(Catalog# : 010813, Cas# :
1035555-63-5
)
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of
Tiotropium Bromide
(Catalog# : 010502, Cas# :
136310-93-5
)
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blo
Tetrabenazine
(Catalog# : 010501, Cas# :
58-46-8
)
Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorde
Tiotropium Bromide
(Catalog# : 010439, Cas# :
139404-48-1
)
Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic
TAS-102
(Catalog# : 010437, Cas# :
733030-01-8
)
TAS-102 is an investigational drug candidate for metastatic colorectal cancer.
Tapentadol hydrochloride
(Catalog# : 010407, Cas# :
175591-09-0
)
Tapentadol Hcl is a centrally acting oral analgesic with opioid and adrenergic activi
Testosterone
(Catalog# : 010405, Cas# :
58-22-0
)
Testosterone is a steroid hormone from the androgen group and is found in mammals, re
Tandutinib
(Catalog# : 123015, Cas# :
387867-13-2
)
Tandutinib is a potent FLT3 antagonist with IC50 of 0.22 M, also inhibits PDGFR and c
Tosedostat
(Catalog# : 123003, Cas# :
238750-77-1
)
Tosedostat is a proprietary orally bioavailable inhibitor of the M1 family of aminope
Trabectedin
(Catalog# : 122948, Cas# :
114899-77-3
)
Trabectedin is a novel antitumour agent of marine origin with potent antitumour activ
TBA-354
(Catalog# : 122934, Cas# :
1257426-19-9
)
TBA-354 is a potent anti-tuberculosis compound; maintains activity against Mycobacter
Terlipressin
(Catalog# : 122929, Cas# :
14636-12-5
)
Terlipressin is an analogue of vasopressin used as a vasoactive drug in the managemen
Tenapanor
(Catalog# : 122919, Cas# :
1234423-95-0
)
Tenapanoris an inhibitor of the sodium-proton exchanger NHE3. Thisantiporter protein
Terameprocol
(Catalog# : 122915, Cas# :
24150-24-1
)
Terameprocol is a synthetic tetra-methylated derivative of nordihydroguaiaretic acid
Tolvaptan
(Catalog# : 122814, Cas# :
150683-30-0
)
Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with
TPT-260
(Catalog# : 122809, Cas# :
769856-81-7
)
TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base f
Topotecan Hydrochloride
(Catalog# : 122522, Cas# :
119413-54-6
)
Topotecan Hcl is the first topoisomerase I-directed cytotoxic agent to enter clinical
6-Thioguanine
(Catalog# : 122512, Cas# :
154-42-7
)
6-Thioguanine belongs to the thiopurine family of drugs that also include mercaptopur
Thiacetazone
(Catalog# : 122408, Cas# :
104-06-3
)
A thiosemicarbazone that is used in association with other antimycobacterial agents i
Tarafenacin
(Catalog# : 122215, Cas# :
385367-47-5
)
Tarafenacin(SVT-40776) is a highly selective M3 muscarinic receptor antagonist (Ki= 0
TASOSARTAN
(Catalog# : 121505, Cas# :
145733-36-4
)
Coming soon!
Torcetrapib
(Catalog# : 121433, Cas# :
262352-17-0
)
Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL
Telatinib
(Catalog# : 121432, Cas# :
332012-40-5
)
Telatinib is a potent inhibitor of VEGFR2/3, c-Kit and PDGFR with IC50 of 6 nM/4 nM,
Telaprevir
(Catalog# : 121423, Cas# :
402957-28-2
)
Telaprevir is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus
Torkinib
(Catalog# : 121420, Cas# :
1092351-67-1
)
PP242 is a selective mTOR inhibitor with IC50 of 8 nM; targets both mTOR complexes wi
TCS 1102
(Catalog# : 121408, Cas# :
916141-36-1
)
TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for
Tedizolid phosphate
(Catalog# : 120713, Cas# :
856867-55-5
)
Tedizolid phosphate is an oxazolidinone drug being developed by Cubist Pharmaceutical
Telotristat
(Catalog# : 120421, Cas# :
1033805-28-5
)
Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an ora
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)