RP-5063（Brilaroxazine）
Catalog No: 822224
CAS Number: 1239729-06-6
Purity: ≧98.0%
RP-5063（Brilaroxazine） is a multimodal modulator of serotonin and dopamine receptors that helps stabilize the serotonin/dopamine system, a key determinant of the pathogenesis of schizophrenia and other associated neuropsychiatric disorders. Brilaroxazine exhibits high binding affinity for the D2, D3, D4, 5-HT1A, 5-HT2A, 5-HT2B and 5-HT7 receptors (Ki, ≤6 nM), and moderate binding affinity for the serotonin transporter (SERT), 5-HT6 receptor, and the nicotinic acetylcholine receptor α4β2 (Ki, ≤50 nM).
For research use only. We do not sell to patients.
Chemical Information
| Name | RP-5063（Brilaroxazine） |
|---|---|
| Iupac Chemical Name | 6-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2H-benzo[b][1,4]oxazin-3(4H)-one |
| Synonyms | RP-5063 ; Brilaroxazine ; RP5063 ; RP 5063 |
| Molecular Formula | C22H25Cl2N3O3 |
| Molecular Weight | 450.36 |
| Smile | ClC1=C(N2CCN(CCCCOC3=CC=C(OCC(N4)=O)C4=C3)CC2)C=CC=C1Cl |
| InChiKey | PMKMNTBZJOXTJW-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28) |
| CAS Number | 1239729-06-6 |
| Related CAS | 1239729-06-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
