Ivacaftor
Catalog No: 52805
CAS Number: 873054-44-5
Purity: 98%
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | Ivacaftor |
|---|---|
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | 392.49 |
| Smile | CC(C)(C)c1cc(c(cc1NC(=O)c2c[nH]c3ccccc3c2=O)O)C(C)(C)C |
| InChiKey | PURKAOJPTOLRMP-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29) |
| CAS Number | 873054-44-5 |
| MDL | MFCD17171361 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO ��75mg/mL Water <1.2mg/mL Ethanol ��3.8mg/mL |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
