INT-747
Catalog No: 122905
CAS Number: 459789-99-2
Purity: 98%
INT-747 is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | INT-747 |
|---|---|
| Iupac Chemical Name | (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
| Synonyms | Obeticholic acid; 6-ECDCA; 6-Ethylchenodeoxycholic acid |
| Molecular Formula | C26H44O4 |
| Molecular Weight | 420.625 |
| Smile | CCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)O)C)C)O |
| InChiKey | ZXERDUOLZKYMJM-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29) |
| CAS Number | 459789-99-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
