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INT-747

Catalog No: 122905
CAS Number: 459789-99-2
Purity: 98% 

INT-747 is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity. 

For research use only. We do not sell to patients.

Chemical Information

NameINT-747
Iupac Chemical Name(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid 
SynonymsObeticholic acid; 6-ECDCA; 6-Ethylchenodeoxycholic acid 
Molecular FormulaC26H44O4 
Molecular Weight420.625 
SmileCCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)O)C)C)O
InChiKeyZXERDUOLZKYMJM-UHFFFAOYSA-N
InChiInChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)
CAS Number459789-99-2
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122905 - INT-747 | CAS 459789-99-2

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