HDM-2006 ( Synonyms: DD205-291)
Catalog No: 25163
CAS Number:
Purity: ≧98.0%
HDM-2006 (DD-205-291) is a a novel PROTAC-based HPK1 degrader with High Potency and Selectivity for Cancer Immunotherapy.
For research use only. We do not sell to patients.
Chemical Information
| Name | HDM-2006 ( Synonyms: DD205-291) |
|---|---|
| Iupac Chemical Name | 1-[2-Chloro-5-(4-[[1-(5-[7-[1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]pyridin-2-yl)piperidin-4-yl]methyl]piperidine-1-carbonyl)phenyl]-1,3-diazinane-2,4-dione |
| Synonyms | HDM-2006 ; HDM2006 ; HDM 2006 ; DD-205-291 ; DD205-291 ; DD 205-291 |
| Molecular Formula | C38H38ClF3N10O3 |
| Molecular Weight | 775.23 |
| Smile | O=C(N1)N(C2=CC(C(N3CCC(CC4CCN(C5=NC=C(C6=CN=C(NC=C7C8=CN(CC(F)(F)F)N=C8)C7=N6)C=C5)CC4)CC3)=O)=CC=C2Cl)CCC1=O |
| InChiKey | NQZCBDOOYGTFSB-UHFFFAOYSA-N |
| InChi | InChI=1S/C38H38ClF3N10O3/c39-29-3-1-25(16-31(29)52-14-9-33(53)48-37(52)55)36(54)50-12-7-24(8-13-50)15-23-5-10-49(11-6-23)32-4-2-26(17-43-32)30-20-45-35-34(47-30)28(19-44-35)27-18-46-51(21-27)22-38(40,41)42/h1-4,16-21,23-24H,5-15,22H2,(H,44,45)(H,48,53,55) |
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| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
