HFY-4A is a HDAC inhibitor. HFY-4A inhibits breast cancer cell proliferation, migration, and invasion, and induces cell apoptosis.
For research use only. We do not sell to patients.
| Name | HFY-4A |
|---|---|
| Iupac Chemical Name | (E)-N-hydroxy-3-(4-(((quinolin-2-ylmethyl)amino)methyl)phenyl)acrylamide |
| Synonyms | HFY-4A; HFY 4A; HFY4A |
| Molecular Formula | C20H19N3O2 |
| Molecular Weight | 333.38 |
| Smile | ONC(/C=C/C(C=C1)=CC=C1CNCC(C=C2)=NC3=C2C=CC=C3)=O |
| InChiKey | ZZAHBOBPSBJKLS-FMIVXFBMSA-N |
| InChi | InChI=1S/C20H19N3O2/c24-20(23-25)12-9-15-5-7-16(8-6-15)13-21-14-18-11-10-17-3-1-2-4-19(17)22-18/h1-12,21,25H,13-14H2,(H,23,24)/b12-9+ |
| CAS Number | 2094810-82-7 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Yin Y, Guan X, Li G, Chen C, Duan Y, Yu Z. The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer. Toxicol Appl Pharmacol. 2023 Nov 1;478:116698. doi: 10.1016/j.taap.2023.116698. Epub 2023 Sep 22. PMID: 37742871.