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Apoptosis
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Cas Index 8
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Cas Index 8
863774-58-7 | Dimethylenastron
(Catalog# : 16122932)
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimeth
850876-88-9 | Danoprevir
(Catalog# : 16070107)
Danoprevir, also known as ITMN-191 and RG-7227, is under development by InterMune Inc
852329-66-9 | Dutogliptin
(Catalog# : 011113)
Dutogliptin is a potent, water soluble, selective and orally bioavailable, boronic ac
847499-27-8 | Delanzomib
(Catalog# : 111302)
Delanzomib is a novel orally-active inhibitor of the chymotrypsin-like activity of th
862574-88-7 | 1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid
(Catalog# : 92211)
Coming soon!
84315-24-2 | 3-(3,5-Difluorophenyl)propionic acid
(Catalog# : 90616)
Coming soon!
89180-50-7 | 5,6-Dichloropyridazin-4-amine
(Catalog# : 81006)
Coming soon!
866405-64-3 | Dorsomorphin
(Catalog# : 52744)
Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inh
89464-63-1 | DMOG
(Catalog# : 52236)
Dimethyloxallyl Glycine(DMOG) is a cell permeable, competitive inhibitor of HIF-PH(HI
82304-99-2 | Ethyl 3-formyl-4-hydroxybenzoate
(Catalog# : 20366)
870843-42-8 | E2012
(Catalog# : 1810231)
E2012 is a γ-secretase modulator (GSM).
848193-68-0 | EX-527 S-enantiomer
(Catalog# : 17011802)
EX-527 S-enantiomer is a potent and selective SIRT1 inhibitor with IC50 of 123 nM; no
848193-69-1 | EX-527 R-enantiomer
(Catalog# : 17011801)
EX-527 R-enantiomer is a negative control of the active form EX-527 S-enantiomer(Spec
828934-41-4 | Etomoxir (Na salt)
(Catalog# : 17011103)
Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) o
858668-07-2 | EMD534085
(Catalog# : 16122938)
EMD534085 is a kinesin inhibitor currently in clinical development.
864821-90-9 | Eluxadoline
(Catalog# : 012005)
Eluxadoline is an orally active mixed opioid receptor (OR) agonist opioid receptor
834153-87-6 | Elagolix
(Catalog# : 121413)
Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist.
866588-11-6 | Ethyl 3-(4-fluorophenyl)-1H-pyrazole-5-carboxylate
(Catalog# : 91707)
Coming soon!
859212-59-2 | Ethyl 3-iodo-4-methylbenzoate
(Catalog# : 80314)
Coming soon!
864070-44-0 | Empagliflozin
(Catalog# : 52720)
Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1
897109-93-2 | F7H inhibitor
(Catalog# : 20556)
F7H is a Frizzled receptor FZD7 antagonist.
821794-92-7 | Fmk
(Catalog# : 188102)
Potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-
864953-29-7 | Fostemsavir
(Catalog# : 1712155)
Fostemsavir, also known as BMS-663068, is a oral, safe and effective HIV-1 attachment
864731-61-3 | Fluralaner
(Catalog# : 178309)
Fluralaner, also known as AH252723, is a systemic insecticide and acaricide that is a
872365-14-5 | Fevipiprant ( NVP-QAW039 )
(Catalog# : 90102)
Fevipiprant (QAW039; NVP-QAW039) is a selective, potent, reversible competitive CRTh2
885060-09-3 | Filanesib
(Catalog# : 16071102)
Filanesib, also known as ARRY-520, is a synthetic, small molecule targeting the kines
808118-40-3 | FG-4592
(Catalog# : 121407)
FG-4592 is an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currentl
83792-48-7 | Fmoc-O-benzyl-L-serine
(Catalog# : 81716)
Coming soon!
865362-74-9 | FR 180204
(Catalog# : 52727)
FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki
849217-64-7 | Foretinib(GSK1363089)
(Catalog# : 51705)
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly forM
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).