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Fevipiprant(NVP-QAW039)

Catalog No.: 16090102
Cas No.: 872365-14-5
Purity : 98% by HPLC/HNMR
16090102 - Fevipiprant(NVP-QAW039) | CAS 872365-14-5

Catalog number : 16090102

CAS number : 872365-14-5

Molecular Formula : C19H17F3N2O4S

Molecular Weight : 426.4

Iupac Chemical Name : 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid

Smile : CC1=C(C=2C(=NC=CC2)N1CC1=C(C=C(C=C1)S(=O)(=O)C)C(F)(F)F)CC(=O)O

InChiKey : GFPPXZDRVCSVNR-UHFFFAOYSA-N

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SynonymsFevipiprant;NVP-QAW039;NVPQAW039;NVP QAW039;
Molecular FormulaC19H17F3N2O4S
Molecular Weight426.4
Appearanceoff-white powder
Purity98% by HPLC/HNMR
SolubilitySoluble in DMSO, not in water
Storage3 years -20℃powder 6 months-80℃in solvent
Shipping ConditionShipped under ambient temperature.
SmileCC1=C(C=2C(=NC=CC2)N1CC1=C(C=C(C=C1)S(=O)(=O)C)C(F)(F)F)CC(=O)O
InChiKeyGFPPXZDRVCSVNR-UHFFFAOYSA-N
InChiInChI=1S/C19H17F3N2O4S/c1-11-15(9-17(25)26)14-4-3-7-23-18(14)24(11)10-12-5-6-13(29(2,27)28)8-16(12)19(20,21)22/h3-8H,9-10H2,1-2H3,(H,25,26)
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Fevipiprant is an oral prostaglandin DP2 receptor (CRTh2) antagonist, in allergic asthma uncontrolled on low-dose inhaled corticosteroids.

1. Hardman C, Chen W etc. Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function. J Allergy Clin Immunol. 2019 Feb 28. pii: S0091-6749(19)30278-7. doi: 10.1016/j.jaci.2019.02.015. [Epub ahead of print]

2. Murillo JC, Dimov V, Gonzalez-Estrada A. An evaluation of fevipiprant for the treatment of asthma: a promising new therapy? Expert Opin Pharmacother. 2018 Dec;19(18):2087-2093. doi: 10.1080/14656566.2018.1540589. Epub 2018 Nov 3.



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