1143532-39-1 | AZD5363 (Catalog# : 71805)AZD5363 is a novel pyrrolopyrimidine derivative, and an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic act
1009298-59-2 | AZD2014 (Catalog# : 71804)1) Sponsor:AstraZeneca 2) Phase:Phase II 3) AZD2014 is a potent (IC50 2.81 nM), selective (inactive against 220 other kinases) inhibitor of mTOR kinase. It Inhibited downstre
1202757-89-8 | AVL-292 (Catalog# : 52770)AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
1232221-74-7 | APY0201 (Catalog# : 52759)APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5
1608125-21-8 | AMG-319 (Catalog# : 52026)AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits b
1401033-86-0 | AMG-925 (Catalog# : 51614)AMG-925 is a potent and orally bioavailable dual inhibitor of CDK4 and FLT3, including many FLT3 mutants reported to date.It inhibits the proliferation of a panel of human tumor
1432660-47-3 | AGI-6780 (Catalog# : 52547)AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2
1177827-73-4 | AP-III-a4 (Catalog# : 52538)ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer c
154235-83-3 | Ampalex (Catalog# : 52524)Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophr
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