AZD8186
Catalog No: 122925
CAS Number: 1627494-13-6
Purity: 98%
AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K (IC50=4 nM) and PI3K (IC50=12 nM) with selectivity over PI3K (IC50=35 nM) and PI3K (IC50=675 nM).
For research use only. We do not sell to patients.
Chemical Information
| Name | AZD8186 |
|---|---|
| Iupac Chemical Name | 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide |
| Synonyms | AZD-8186 |
| Molecular Formula | C24H25F2N3O4 |
| Molecular Weight | 457.470 |
| Smile | CC(C1=C2C(=CC(=C1)C(=O)N(C)C)C(=O)C=C(O2)N3CCOCC3)NC4=CC(=CC(=C4)F)F |
| InChiKey | LMJFJIDLEAWOQJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3 |
| CAS Number | 1627494-13-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
