1421373-65-0 | AZD9291 (Catalog# : 52306)AZD9291 is an oral, irreversible, and mutant-selectiveEGFRinhibitor withIC50of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR, respectively. P
1204144-28-4 | AZD1208 (Catalog# : 51702)AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that effectively inhibits all three isoforms at <5 nM or <150 nM in enzyme and cell assays,
1124329-14-1 | AZ3146 (Catalog# : 51903)AZ3146 is a selectiveMps1inhibitor withIC50of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
1056901-62-2 | AT13148 (Catalog# : 51902)AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. AT13148 exerted potent cytotoxic and anti-proliferative activities against a panel human gastr
1093108-50-9 | BI-671800 (Catalog# : 191213)BI-671800 is a CRTH2 antagonist that treats patients with asthma. BI 671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in
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