A66 is a potent and specific p110 inhibitor with IC50 of 32 nM, >100 fold selectivity for p110 over other class-I PI3K isoforms.
For research use only. We do not sell to patients.
| Name | A66 |
|---|---|
| Iupac Chemical Name | (2S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide |
| Synonyms | A-66; A 66 |
| Molecular Formula | C17H23N5O2S2 |
| Molecular Weight | 393.52 |
| Smile | CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CSC(=N3)C(C)(C)C |
| InChiKey | HBPXWEPKNBHKAX-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24) |
| CAS Number | 1166227-08-2 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |