武汉永璨生物科技有限公司
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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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On Sale
中间体
技术服务
定制合成
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 S
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产品名字索引 S
Sapitinib(AZD8931)
(Catalog# : 60301, Cas# :
848942-61-0
)
AZD8931(Sapitinib)is a novel potent reversible small molecule epidermal growth factor
SU6656
(Catalog# : 52754, Cas# :
330161-87-0
)
SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC
SBE13 Hydrochloride
(Catalog# : 52751, Cas# :
1052532-15-6
)
SBE13 Hcl is a potent and selective PLK1 with IC50 of 0.2 nM; no inhibition om Aurora
SGI-1027
(Catalog# : 52737, Cas# :
1020149-73-8
)
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC5
SB225002
(Catalog# : 52714, Cas# :
182498-32-4
)
SB225002 is a potent and selective non-peptide inhibitor of CXCR2 with IC50 of 22 nM;
SU9516
(Catalog# : 52579, Cas# :
377090-84-1
)
SU-9516 is a selective CDK2 inhibtor with IC50 of 22 nM; less potent for CDK1/CDK4(IC
SCH900776
(Catalog# : 52575, Cas# :
891494-63-6
)
SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kina
Selumetinib
(Catalog# : 52571, Cas# :
606143-52-6
)
Selumetinib (AZD6244; ARRY-142886) is a potent, highly selective MEK1 inhibitor with
Siramesine hydrochloride
(Catalog# : 52549, Cas# :
224177-60-0
)
Siramesine(Lu 28-179) Hcl is a selective sigma-2 receptor agonist, which has been sho
Siramesine
(Catalog# : 52548, Cas# :
147817-50-3
)
Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown t
S1RA
(Catalog# : 52546, Cas# :
878141-96-9
)
S1RA(E-52862) is a potent and selective sigma-1 receptor(1R, Ki=17 nM) antagonist, sh
SMI-4a
(Catalog# : 52537, Cas# :
438190-29-5
)
SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM fo
SKLB610
(Catalog# : 52536, Cas# :
1125780-41-7
)
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kin
StemRegenin 1
(Catalog# : 52531, Cas# :
1227633-49-9
)
StemRegenin 1(SR1) is an antagonist of the aryl hydrocarbon receptor.SR1 is the first
S0859
(Catalog# : 52507, Cas# :
1019331-10-2
)
S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recover
SRPIN340
(Catalog# : 52210, Cas# :
218156-96-8
)
SRPIN340 is a serine/arginine-rich protein kinase (SRPK)-specific inhibitor with an I
5S rRNA modificator
(Catalog# : 52243, Cas# :
1415238-77-5
)
5S rRNA modificator is a suitable electrophile for 2-hydroxyl acylation on structured
SB431542
(Catalog# : 52312, Cas# :
301836-41-9
)
SB431542 is a potent and selective inhibitor ofALK5withIC50of 94 nM, 100-fold more se
Salirasib
(Catalog# : 52106, Cas# :
162520-00-5
)
Salirasib(S-Farnesylthiosalicylic aci) is an S-farnesyl cysteine analog that interfer
SNS-032 ( BMS-387032 )
(Catalog# : 52105, Cas# :
345627-80-7
)
SNS-032 has firstly been described as a selective inhibitor ofCDK2withIC50of 48 nM an
SNS-314 Mesylate
(Catalog# : 52102, Cas# :
1057249-41-8
)
SNS-314 Mesylate is a potent and selective inhibitor ofAurora A,Aurora BandAurora Cwi
Semaxanib (SU5416)
(Catalog# : 51803, Cas# :
204005-46-9
)
Semaxanib (SU5416) is a potent and selectiveVEGFR(Flk-1/KDR) inhibitor withIC50of 1.2
SSR128129E
(Catalog# : 51608, Cas# :
848318-25-2
)
SSR128129E is an orally-active and allostericFGFR1inhibitor withIC50of 1.9 M, while n
SRT1720
(Catalog# : 52007, Cas# :
1001645-58-4
)
SRT1720 is a selectiveSIRT1activator withEC50of 0.16 M, but is >230-fold less pote
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
PF-06835919 ( MDK-1846 )
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
FHD-286
(Catalog# : 20471, Cas# :
2671128-05-3
)
FHD-286 is an oral, small-molecule, selective, allosteric inhibitor of BRG1 and BRM i
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 是具有血脑屏障渗透性的 MAPK 通路分子胶,能够抑制 RAF 磷
PHGDH-IN-3
(Catalog# : 25077, Cas# :
2893778-31-7
)
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor.
CFT1946
(Catalog# : 25078, Cas# :
2882165-79-7
)
CFT1946 是一种口服生物可利用的小分子降解剂,可降解实体瘤中的
异硫蓝
(Catalog# : 178017, Cas# :
68238-36-8
)
Isosulfan blue 是一种用于淋巴管造影中淋巴管识别的蓝色染料。Isos
HC-7366
(Catalog# : 25076, Cas# :
2803470-63-3
)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
Soquelitinib ( CPI-818 )
(Catalog# : 20671, Cas# :
2226636-04-8
)
Soquelitinib(CPI-818)是一种高度选择性的共价白细胞介素-2诱导的T
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
LLL12
(Catalog# : 25075, Cas# :
1260247-42-4
)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration