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SNS-032(BMS-387032)

Catalog No.: 52105
Cas No.: 345627-80-7
Purity : 98% 
52105 - SNS-032(BMS-387032) | CAS 345627-80-7

Catalog number : 52105

CAS number : 345627-80-7

分子式 : C17H24N4O2S2 

分子量 : 380.53 

Iupac 化学名称 : N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide 

Smile : C(C)(C)(C)C1=CN=C(O1)CSC1=CN=C(S1)NC(=O)C1CCNCC1

InChiKey : OUSFTKFNBAZUKL-UHFFFAOYSA-N

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同义词SNS-032,BMS-387032; SNS032; SNS 032;BMS 387032;BMS387032
英文同义词SNS-032,BMS-387032; SNS032; SNS 032;BMS 387032;BMS387032
分子式C17H24N4O2S2 
分子量380.53 
外观off-white solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileC(C)(C)(C)C1=CN=C(O1)CSC1=CN=C(S1)NC(=O)C1CCNCC1
InChiKeyOUSFTKFNBAZUKL-UHFFFAOYSA-N
InChiInChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)
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SNS-032 has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. Phase 1. 

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