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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
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Cytoskeletal Signaling
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Cas号索引 1
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Cas号索引 1
1422269-30-4 | ML-18
(Catalog# : 179810)
ML-18是蛙皮素受体亚型3(BRS-3)拮抗剂(IC50 = 4.8μm)。ML-18抑制肺
1207253-08-4 | MK-1064
(Catalog# : 16123054)
MK-1064是一种有效的、选择性和口服的Orexin OX2受体拮抗剂,用于治
1857417-13-0 | MI-503
(Catalog# : 178908)
MI-503是一种具有IC50为14.7 nM的有效和选择性的menin - mll抑制剂。在
1206799-15-6 | Merestinib (LY2801653)
(Catalog# : 178905)
Merestinib,又名LY2801653,是一种可口服的小分子抑制剂,原癌基因
1628317-18-9 | MI-463
(Catalog# : 17031006)
MI-463是一种Menin-MLL强力抑制剂,与IC50值15.3 nM相互作用。
1221186-53-3 | ML-265
(Catalog# : 17030804)
ML265是一个强有力的PKM2活化剂诱导四聚体,降低肿瘤的形成和大小
1346528-06-0 | ML241
(Catalog# : 17030714)
ML241是一种p97 ATPase有效的选择性抑制剂。ML241抑制p97 ATPase的IC(50)值
198821-22-6 | Merimepodib
(Catalog# : 17030308)
Merimepodib, 也称为VX-497,是有效的口服生物IMPDH抑制剂,它可以抑制
1550008-55-3 | ML-264
(Catalog# : 17030302)
ML-264是一种Krüppel-like因子5(KLF5)抑制剂,能有效抑制结直肠癌的生
1030612-90-8 | MK-8245
(Catalog# : 17030109)
MK-8245是一种有效的、以肝脏为靶点的SCD抑制剂,具有临床前抗糖
1268454-23-4 | MLN-1117
(Catalog# : 17030101)
Serabelisib(又名MLN1117,INK1117,TAK- 117)是一类具有潜在抗肿瘤活性的磷
1404437-62-2 | ML-281
(Catalog# : 17022811)
ML-281是一种有效的选择性STK33抑制剂(IC50 = 14nm)。与其他STK33抑制剂
1502816-23-0 | MS049
(Catalog# : 17021313)
MS049是PRMT4和PRMT6的一种有效的选择性抑制剂,IC50分别为34 nM和43 n
1313883-00-9 | Miransertib(ARQ 092)
(Catalog# : 17021301)
ARQ 092是一种新型的口服生物可用性和选择性AKT通路抑制剂,在晚
1399840-35-7 | MT-DADMe-ImmA(MTDIA HCl)
(Catalog# : 712101)
MT-DADMe-ImmA(MTDIA盐酸盐)是一种新型的MTAP抑制剂,具有治疗头颈部和
110448-33-4 | ML-7
(Catalog# : 17011107)
ML-7是平滑肌肌球蛋白轻链激酶的抑制剂(MLCK),Ki值为0.3μM。
1005264-47-0 | MX69
(Catalog# : 17011105)
MX69是一种MDM2/XIAP抑制剂, 用于治疗癌症。
115104-28-4 | MK-571 sodium salt
(Catalog# : 16123055)
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the bindin
1445993-26-9 | Mivebresib
(Catalog# : 16123052)
Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-cont
1198097-97-0 | Mirin
(Catalog# : 16123049)
Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor.
1047953-91-2 | MI-2 (MALT1 inhibitor)
(Catalog# : 16123047)
MI-2 is a MALT1 inhibitor (IC50 = 5.84 M). MI-2 binds directly to MALT1 and irreversi
110044-82-1 | MG-101
(Catalog# : 16123046)
MG-101, also known as Calpain Inhibitor I and ALLN, is a calpain inhibitor (IC50 = 0.
139504-50-0 | Mertansine (DM1)
(Catalog# : 16123045)
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2-deacetyl-N2-(3-mercap
129831-99-8 | MC-976
(Catalog# : 16122832)
MC-976 is an Vitamin D3 derivative.
115103-85-0 | MK571
(Catalog# : 161227105)
MK-571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor)
1572414-83-5 | ML323
(Catalog# : 16122790)
ML323 is a highly potent and selective USP1-UAF1 inhibitor with IC50 of 76 nM.ML323 i
1190378-57-4 | MRT67307
(Catalog# : 16122745)
MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, re
1038915-73-9 | MK-4827(Niraparib) tosylate
(Catalog# : 16122717)
MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8
1227962-62-0 | Marinopyrrole A
(Catalog# : 6111403)
Marinopyrrole (Maritoclax) is a novel and specific Mcl-1 inhibitor with an IC50 value
1338824-21-7 | ML224
(Catalog# : 61116)
ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimula
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
2671128-05-3 | FHD-286
(Catalog# : 20471)
FHD-286 is an oral, small-molecule, selective, allosteric inhibitor of BRG1 and BRM i
3002056-30-3 | NST-628
(Catalog# : 24058)
NST-628 是具有血脑屏障渗透性的 MAPK 通路分子胶,能够抑制 RAF 磷
2893778-31-7 | PHGDH-IN-3
(Catalog# : 25077)
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor.
2882165-79-7 | CFT1946
(Catalog# : 25078)
CFT1946 是一种口服生物可利用的小分子降解剂,可降解实体瘤中的
68238-36-8 | 异硫蓝
(Catalog# : 178017)
Isosulfan blue 是一种用于淋巴管造影中淋巴管识别的蓝色染料。Isos
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
2226636-04-8 | Soquelitinib ( CPI-818 )
(Catalog# : 20671)
Soquelitinib(CPI-818)是一种高度选择性的共价白细胞介素-2诱导的T
2230263-60-0 | Crelosidenib
(Catalog# : 24101)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration