MDK7229, also known as MD2-IN-1 is a MD2 (Myeloid differentiation protein 2) inhibitor. MDK7229 locked the LPS-induced activation of TLR4/MD2 -downstream pro-inflammatory MAPKs/NF-κB signaling pathways.
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| 名称 | MDK7229 |
|---|---|
| Iupac 化学名称 | (E)-1-(3,4-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one |
| 同义词 | MD2-IN-1; MDK7229; MDK 7229; MDK 7229. |
| 英文同义词 | MD2-IN-1; MDK7229; MDK 7229; MDK 7229. |
| 分子式 | C20H22O6 |
| 分子量 | 358.39 |
| Smile | COC1=C(OC)C(OC)=CC(/C=C/C(C2=CC=C(OC)C(OC)=C2)=O)=C1 |
| InChiKey | ZKYRYELHPFTZTI-SOFGYWHQSA-N |
| InChi | InChI=1S/C20H22O6/c1-22-16-9-7-14(12-17(16)23-2)15(21)8-6-13-10-18(24-3)20(26-5)19(11-13)25-4/h6-12H,1-5H3/b8-6+ |
| Cas号 | 111797-22-9 |
| 相关CAS号 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid to white solid |
|---|---|
| 纯度 | >98% |
| 存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| 可溶性 | Soluble in DMSO, not in water |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |