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WDR5-0103

Catalog No: 16122845
CAS Number: 890190-22-4
Purity: 98% 

WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 M). WD repeat domain 5 (WDR5) plays an important role in various biological functions through the epigenetic regulation of gene transcription. WDR5 may have oncogenic effect and WDR5-mediated H3K4 methylation plays an important role in leukemogenesis. 

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Chemical Information

NameWDR5-0103
Iupac Chemical NameWDR5-0103 
SynonymsWDR 5-0103; WDR-5-0103; WDR50103; WDR-50103; WDR 50103; WD-Repeat Protein 5-0103 
Molecular FormulaC21H25N3O4 
Molecular Weight383.448 
InChiKey
InChi
CAS Number890190-22-4
Related CAS

Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122845 - WDR5-0103 | CAS 890190-22-4

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