Torkinib
Catalog No: 121420
CAS Number: 1092351-67-1
Purity: 98%
PP242 is a selective mTOR inhibitor with IC50 of 8 nM; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3K or PI3K//, respectively; also showed slightly weaker activity against BRD4 (Kd= 1.7 uM).
For research use only. We do not sell to patients.
Chemical Information
| Name | Torkinib |
|---|---|
| Iupac Chemical Name | (2E)-2-(4-amino-1-propan-2-yl-2H-pyrazolo[3,4-d]pyrimidin-3-ylidene)indol-5-ol |
| Synonyms | PP242; PP-242 ;Torkinib; PP 242 |
| Molecular Formula | C16H16N6O |
| Molecular Weight | 308.338 |
| Smile | CC(C)N1C2=C(C(=C3C=C4C=C(C=CC4=N3)O)N1)C(=NC=N2)N |
| InChiKey | MTICIDWIKCANDD-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,21,23H,1-2H3,(H2,17,18,19) |
| CAS Number | 1092351-67-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
