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LDN-57444

Catalog No: 110606
CAS Number: 668467-91-2
Purity: 98% 

LDN-57444 is a Uch-L1 inhibitor with Ki= 0.4 M. Ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) is an intracellular protein abundantly expressed in neurons, and a mutation in UCH-L1 has been identified in familial Parkinson's disease. 

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Chemical Information

NameLDN-57444
Iupac Chemical Name(Z)-3-(acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)indolin-2-one 
SynonymsLDN 57444; LDN57444; UCH-L1 Inhibitor 
Molecular FormulaC17H11Cl3N2O3 
Molecular Weight397.64 
SmileO=C1N(CC2=CC(Cl)=CC=C2Cl)C3=C(C=C(Cl)C=C3)/C1=N/OC(C)=O
InChiKeyOPQRFPHLZZPCCH-PGMHBOJBSA-N
InChiInChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-
CAS Number668467-91-2
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

110606 - LDN-57444 | CAS 668467-91-2

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