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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index A
AZD1283
(Catalog# : 52573, Cas# :
919351-41-0
)
AZD1283 is a potent antagonist of the P2Y12 receptor with EC50 of 3.0 ug/kg/min, TI &
Apoptosis Activator 2
(Catalog# : 52551, Cas# :
79183-19-0
)
Apoptosis Activator 2 is a potent apoptosis activator; increases procaspase-9 process
AGI-6780
(Catalog# : 52547, Cas# :
1432660-47-3
)
AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitr
AP-III-a4
(Catalog# : 52538, Cas# :
1177827-73-4
)
ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analog
AWD 131-138
(Catalog# : 52533, Cas# :
188116-07-6
)
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist
Ampalex
(Catalog# : 52524, Cas# :
154235-83-3
)
Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an
AR-A014418
(Catalog# : 52523, Cas# :
487021-52-3
)
AR-A014418 is a selective and effective GSK3 inhibitor with an IC 50 value of 104 +/-
AG 18
(Catalog# : 52504, Cas# :
118409-57-7
)
AG-18(RG-50810; Tyrphostin A23) inhibits EGFR with IC50 of 40 M.
AG-1478
(Catalog# : 52222, Cas# :
153436-53-4
)
AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activ
Atglistatinc
(Catalog# : 52240, Cas# :
1469924-27-3
)
Atglistatin is a highly potent, selective and competitive inhibitor of adipose trigly
ATB-346
(Catalog# : 52232, Cas# :
1226895-20-0
)
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly r
Afobazole
(Catalog# : 52242, Cas# :
173352-21-1
)
Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effe
AT7519
(Catalog# : 52314, Cas# :
844442-38-2
)
AT7519 is a multi-CDKinhibitor for CDK1, 2, 4, 6 and 9 withIC50of 10-210 nM. It is le
Aceclofenac
(Catalog# : 51914, Cas# :
89796-99-6
)
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.
Alectinib(CH5424802)
(Catalog# : 51907, Cas# :
1256580-46-7
)
Alectinibis a second-generation, orally active, potent and highly selective inhibitor
AZD1152-HQPA
(Catalog# : 51904, Cas# :
722544-51-6
)
Barasertib (AZD1152-HQPA) is a highly selectiveAurora Binhibitor withIC50of 0.37 nM,
AZD6482
(Catalog# : 51603, Cas# :
1173900-33-8
)
AZD6482 is aPI3Kinhibitor withIC50of 10 nM, 8-, 87- and 109-fold more selective to PI
AZD1208
(Catalog# : 51702, Cas# :
1204144-28-4
)
AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that
AZ3146
(Catalog# : 51903, Cas# :
1124329-14-1
)
AZ3146 is a selectiveMps1inhibitor withIC50of ~35 nM, contributes to recruitment of C
AT13148
(Catalog# : 51902, Cas# :
1056901-62-2
)
AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. A
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibito
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010 is a freely brain-penetrant, potent, and selective CHK1 inhibitor.
Tert-butyl 4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin is a small molecule that inhibits formation of Lp(a) by interfering with t
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) is a blood-brain barrier-penetrant and orally active MAT2
AD-8007
(Catalog# : 26A018, Cas# :
1497439-74-3
)
AD-8007 is a selective and brain-penetrant inhibitor of acetyl CoA synthase 2 (ACSS2).
ZY-444
(Catalog# : 26A020, Cas# :
1802650-31-2
)
ZY-444 is an anti-cancer agent by inhibiting PC ( pyruvate carboxylase ) activity.
AD-5584
(Catalog# : 26A019, Cas# :
2306525-79-9
)
AD-5584 is a novel brain-permeable ACSS2 inhibitors.
IDB-003
(Catalog# : 26A017, Cas# :
3079716-11-0
)
IDB-003 inhibits MDA-MB-231 tumor growth in vivo.
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)