AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.
For research use only. We do not sell to patients.
Chemical Information
| Name | AG-1478 |
| Molecular Formula | C16H14ClN3O2 |
| Molecular Weight | 315.75 |
| Smile | COc1cc2c(cc1OC)ncnc2Nc3cccc(c3)Cl |
| InChiKey | GFNNBHLJANVSQV-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) |
| CAS Number | 153436-53-4 |
| MDL | MFCD00270914 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
| Handling | |
| HS Code | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |