AZ3146
Catalog No: 51903
CAS Number: 1124329-14-1
Purity: 98%
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
For research use only. We do not sell to patients.
Chemical Information
| Name | AZ3146 |
|---|---|
| Iupac Chemical Name | 9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one |
| Synonyms | AZ3146 ; AZ-3146 ; AZ 3146 |
| Molecular Formula | C24H32N6O3 |
| Molecular Weight | 452.55 |
| Smile | C1(CCCC1)N1C2=NC(=NC=C2N(C1=O)C)NC1=C(C=C(C=C1)OC1CCN(CC1)C)OC |
| InChiKey | YUKWVHPTFRQHMF-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H32N6O3/c1-28-12-10-17(11-13-28)33-18-8-9-19(21(14-18)32-3)26-23-25-15-20-22(27-23)30(24(31)29(20)2)16-6-4-5-7-16/h8-9,14-17H,4-7,10-13H2,1-3H3,(H,25,26,27) |
| CAS Number | 1124329-14-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
