396091-73-9 | Pasireotide (Catalog# : 61115)Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.
371935-74-9 | PI-103 (Catalog# : 160926002)It inhibits ATR and ATM only at much higher concentrations (IC50= 850 and 920 nM, respectively) and exhibits little activity towards a panel of more than 40 other kinases even at
391210-00-7 | PD318088 (Catalog# : 010414)PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
382180-17-8 | Pyroxamide (Catalog# : 121802)Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic properties, which inhibits histone deacetylases involved in transcription; induces hyperacetylation of
328023-11-6 | Rbin-1 (Catalog# : 1710902)Rbin-1(ribozinoindole-1) is a potent chemical inhibitor of eukaryotic ribosome assembly. It inhibits recombinant full-length Mdn1's ATPase activity in vitro. Ribozinoindoles ar
307538-42-7 | SMER28 (Catalog# : 17011709)SMER28 is a small molecule modulator of autophagy, inducing autophagy independently of rapamycin in mammalian cells. SMER28, acting via an mTOR-independent mechanism, prevented t
312636-16-1 | SKI II (Catalog# : 6111526)SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 M for SK1 and 45 M for SK2. SKI II inhibits cell proliferation by suppressing the Wnt/-caten
305834-79-1 | SC79 (Catalog# : 161009025)Akt Activator II, SC79, CAS 305834-79-1, is a cell-permeable compound that interacts with Akt PH domain PIP3 binding pocket and makes it more susceptible to phosphorylation by up
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