374913-63-0 | Madrasin (Catalog# : 16122830)Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin stalls spliceosome assembly at the A complex.
312271-03-7 | M2I-1 (Catalog# : 16122829)M2I-1, also known as Mad2 Inhibitor-1, is Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. M2I-1 disturbs conformational dynamics of Mad2
326914-06-1 | MHY1485 (Catalog# : 52219)MHY1485 is a mTOR activator; inhibits the autophagic process by inhibition of fusion between autophagosomes and lysosomes leading to the accumulation of LC3II protein and enlarge
348575-88-2 | Optovin (Catalog# : 102609)Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish.
301353-96-8 | P7C3 (Catalog# : 16122837)P7C3 is a proneurogenic, neuroprotective agent. P7C3 protects newborn neurons from apoptotic cell death, and promotes neurogenesis in mice and rats in the subgranular zone of the
396091-73-9 | Pasireotide (Catalog# : 61115)Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.
371935-74-9 | PI-103 (Catalog# : 160926002)It inhibits ATR and ATM only at much higher concentrations (IC50= 850 and 920 nM, respectively) and exhibits little activity towards a panel of more than 40 other kinases even at
391210-00-7 | PD318088 (Catalog# : 010414)PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.