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IU1

Catalog No.: 51637
Cas No.: 314245-33-5
Purity : 98% 

IU1 is a reversible and specific inhibitor of proteasome-associating Usp14. It does not inhibit other deubiquitinating enzymes of the 26S proteasome. It partially inhibits the ubiquitin chain trimming activity of the 26S proteasome, which could function to stimulate the degradation of some proteasomal substrates.

 

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Chemical Information

NameIU1
Iupac Chemical Name1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone 
SynonymsIU1 
Molecular FormulaC18H21FN2O 
Molecular Weight300.37 
SmileCC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3
InChiKeyJUWDSDKJBMFLHE-UHFFFAOYSA-N
InChiInChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
CAS Number314245-33-5
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationlight yellow solid 
Purity98% 
Storage3 years -20ºCpowder 
Solubility5mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51637 - IU1 | CAS 314245-33-5

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