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PI3K/Akt/mTOR
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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Cas Index 7
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Cas Index 7
706779-91-1 | Pimavanserin
(Catalog# : 120809)
Pimavanserin is an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x
714272-27-2 | Plinabulin
(Catalog# : 52603)
Plinabulin (NPI-2358) is a vascular disrupting agents (VDA) against tubulin-depolymer
775304-57-9 | PTC124c
(Catalog# : 52231)
PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not nor
746667-48-1 | Quinoxaline
(Catalog# : 16062205)
Quinoxaline
741713-40-6 | R547
(Catalog# : 1811151)
R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI
784210-87-3 | RGB-286638
(Catalog# : 611924)
RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin
737789-87-6 | Relugolix
(Catalog# : 16060701)
Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH)
784210-88-4 | RGB-286638 free base
(Catalog# : 122917)
RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin
791098-84-5 | (R)-1-(2,4-Difluorophenyl)ethanamine
(Catalog# : 91131)
Coming soon!
771465-40-8 | (1R)-1-(3,5-difluorophenyl)ethanamine
(Catalog# : 91114)
Coming soon!
790208-54-7 | (1R)-6-fluoro-2,3-dihydro-1H-inden-1-amine
(Catalog# : 91111)
Coming soon!
737713-28-9 | [(R)-1-(3,5-Dimethylphenyl)ethyl]amine
(Catalog# : 91108)
Coming soon!
72925-16-7 | (R)-1-Boc-pyrrolidine-3-carboxylic Acid
(Catalog# : 83128)
Coming soon!
7764-95-6 | (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
(Catalog# : 81020)
Coming soon!
755037-03-7 | Regorafenib
(Catalog# : 52722)
Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDG
792173-99-0 | SB-334867 free base
(Catalog# : 185114)
SB-334867 is an orexin antagonist.
704869-38-5 | SUN11602
(Catalog# : 17030603)
SUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of
760981-83-7 | Solithromycin
(Catalog# : 17011710)
Solithromycin, also known as CEM-101 and OP-1068, is a ketolide antibiotic undergoing
72873-74-6 | SKF-86002
(Catalog# : 011308)
SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM.
724741-75-7 | STF31
(Catalog# : 122831)
STF31 is a potent glucose transporter 1 (GLUT1).
76279-30-6 | (S)-1-(o-Tolyl)ethanamine
(Catalog# : 90717)
Coming soon!
75747-14-7 | Tanespimycin
(Catalog# : 16070805)
Tanespimycin, also known as 17-AAG, is an orally bioavailable, small-molecule inhibit
752187-80-7 | Taprenepag(CP-544326)
(Catalog# : 652601)
Taprenepag is the active metabolite of PF-04217329.
733030-01-8 | TAS-102
(Catalog# : 010437)
TAS-102 is an investigational drug candidate for metastatic colorectal cancer.
769856-81-7 | TPT-260
(Catalog# : 122809)
TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base f
74513-16-9 | TETRAHYDROPENTALENE-2,5-DIONE
(Catalog# : 82715)
Coming soon!
79183-37-2 | VU0119498
(Catalog# : 2071547)
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 p
705260-08-8 | Vorapaxar sulfate
(Catalog# : 178307)
Vorapaxar, also known as SCH 530348, is a thrombin receptor (protease-activated recep
755038-65-4 | Volasertib
(Catalog# : 20178219)
Volasertib, also known as BI-6727, is a dihydropteridinone Polo-like kinase 1 (Plk1)
745833-23-2 | VX-702
(Catalog# : 16070804)
VX-702, one of a series of second-generation, is an orally active p38 MAP kinase inhi
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).