552292-08-7 | Rolapitant (Catalog# : 122804)Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CIN
52029-86-4 | STO-609 (Catalog# : 17021319)STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KK and CaM-KK isoforms, with Ki val
522650-83-5 | SW044248 (Catalog# : 17011714)SW044248 is a potent and selective Topoisomerase I inhibitor. SW044248 killed approximately 15% of a panel of 74 NSCLC cell lines and was nontoxic to immortalized human bronchial
521984-48-5 | SIS3 (Catalog# : 16122721)SIS3, a novel specific inhibitor of Smad3, inhibits TGF- and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling p
502632-66-8 | Sonolisib (Catalog# : 122944)Sonolisib is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential. antineoplastic activity.
594839-88-0 | Tafamidis (Catalog# : 193182)Tafamidis, Tafamidis, also known as Fx-1006 or PF-06291826, is a drug for the amelioration of transthyretin-related hereditary amyloidosis (also familial amyloid polyneuropathy,
507475-17-4 | TPCA-1 (Catalog# : 17031308)TPCA-1 is a potent IKK-2 inhibitor. TPCA-1 is also an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation in vivo. It selectively repressed proliferati
52-24-4 | Thiotepa (Catalog# : 17031304)Thiotepa is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity.
530141-72-1 | T-5224 (Catalog# : 16070909)T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and
565460-15-3 | URB602 (Catalog# : 17030711)URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 M for the rat brain enzyme. Pretreatment with the monoacylglycerol lipase inhibitor URB602
58970-76-6 | Ubenimex (Catalog# : 17030602)Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipop
537672-41-6 | UF-010 (Catalog# : 16122842)UF-010 is a Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 M for HDACs 3, 2, 1 and 8, respectively). UF010 inhibits cancer cell proliferation via class I HDAC inh
518303-20-3 | UMI-77 (Catalog# : 010426)UMI-77 is a novel selective Mcl-1 SMI inhibitor. UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2