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AZD2014(Vistusertib)

Catalog No: 71804
CAS Number: 1009298-59-2
Purity: 98% by HPLC 

AZD2014 is a potent (IC50 2.81 nM), selective (inactive against 220 other kinases) inhibitor of mTOR kinase. It Inhibited downstream targets of both mTORC1 (pS6 and p4EBP1) and mTORC2 (pAKT s473) in several in vitro models in a dose- and time-dependent manner.

For research use only. We do not sell to patients.

Chemical Information

NameAZD2014(Vistusertib)
Iupac Chemical Name3-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-N-methylbenzamide 
SynonymsAZD 2014;AZD-2014;AZD2014;Vistusertib
Molecular FormulaC25H30N6O3 
Molecular Weight462.5 
SmileO=C(NC)C1=CC=CC(C2=CC=C3C(N4[C@@H](C)COCC4)=NC(N5[C@@H](C)COCC5)=NC3=N2)=C1
InChiKeyJUSFANSTBFGBAF-IRXDYDNUSA-N
InChiInChI=1S/C25H30N6O3/c1-16-14-33-11-9-30(16)23-20-7-8-21(18-5-4-6-19(13-18)24(32)26-3)27-22(20)28-25(29-23)31-10-12-34-15-17(31)2/h4-8,13,16-17H,9-12,14-15H2,1-3H3,(H,26,32)/t16-,17-/m0/s1
CAS Number1009298-59-2
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% by HPLC 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

71804 - AZD2014(Vistusertib) | CAS 1009298-59-2

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