Zegocractin (CM-4620, Auxora(TM)) is a small-molecule inhibitor of the calcium release-activated calcium channel protein 1 (CRAC channel, ORAI1) .
For research use only. We do not sell to patients.
| Name | Zegocractin ( CM-4620 ) |
|---|---|
| Iupac Chemical Name | N-(5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide |
| Synonyms | CM-4620 ; CM 4620 ; CM4620 ; Zegocractin |
| Molecular Formula | C19H11ClF3N3O3 |
| Molecular Weight | 421.7602 |
| Smile | O=C(NC1=NC=C(C2=C(Cl)C=C(OC(F)(F)O3)C3=C2)N=C1)C4=C(C)C=CC=C4F |
| InChiKey | QQMKTHUGOQDEIL-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H11ClF3N3O3/c1-9-3-2-4-12(21)17(9)18(27)26-16-8-24-13(7-25-16)10-5-14-15(6-11(10)20)29-19(22,23)28-14/h2-8H,1H3,(H,25,26,27) |
| CAS Number | 1713240-67-5 |
| Related CAS | 1713240-67-5 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Solubility:Soluble in DMSO |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | Orai1 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |