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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Pyrimidines
Quinolines
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产品名字索引 E
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产品名字索引 E
EPZ015666
(Catalog# : 011309, Cas# :
1616391-65-1
)
EPZ-015666 是一种强效、选择性的口服生物药,PRMT5抑制剂与Ki为5 nm
EED226
(Catalog# : 178311, Cas# :
2083627-02-3
)
EED226是一种强效、选择性抑制剂,口服生物EED抑制剂。在EZH2MUT临
厄达替尼(JNJ-42756493)
(Catalog# : 651701, Cas# :
1346242-81-6
)
Erdafitinib(JNJ-42756493) is a potent and selective panfibroblast growth factor recep
Ethyl 2-cyclohexyl-2-oxoacetate
(Catalog# : 178157, Cas# :
13275-31-5
)
Ethyl 2-cyclohexyl-2-oxoacetate
E7449
(Catalog# : 178903, Cas# :
1140964-99-3
)
E7449是一种可口服的小分子抑制剂,核酶聚(ADP-核糖)聚合酶(PARP)1和
Elenbecestat ( E2609 )
(Catalog# : 2017878, Cas# :
1388651-30-6
)
Elenbecestat是一种β-Site淀粉样前体蛋白裂解酶BACE)抑制剂,主要用
依托泊苷磷酸酯
(Catalog# : 20178213, Cas# :
117091-64-2
)
依托泊苷磷酸盐是一种半合成足叶草毒素的磷酸盐。
Elamipretide
(Catalog# : 20178210, Cas# :
736992-21-5
)
Elamipretide, 也称为MTP-131或D-Arg-Dmt-Lys-Phe-NH2,是一种心肌过氧化酶抑
[(1S)-2-(3,5-二氟苯基)-1-[(2S)-环氧乙烷基]乙基]氨基甲酸叔丁酯
(Catalog# : 20177314, Cas# :
388071-27-0
)
[(1S)-2-(3,5-二氟苯基)-1-[(2S)-环氧乙烷基]乙基]氨基甲酸叔丁酯
Etrasimod
(Catalog# : 17031018, Cas# :
1206123-37-6
)
Etrasimod,也被称为APD334,是一种多功能S1P1受体的功能拮抗剂,用
eFT-508
(Catalog# : 17031010, Cas# :
1849590-01-7
)
eFT-508 (eFT508)是一种有效且选择性的MNK1 / 2抑制剂,可能导致肿瘤细
盐酸Epetraborole
(Catalog# : 17022806, Cas# :
1234563-16-6
)
盐酸Epetraborole是一种新型的leucyl - trna合成酶(LeuRS)抑制剂。
依利格鲁司特
(Catalog# : 17022718, Cas# :
491833-29-5
)
依利格鲁司特, 也叫Genz-112638, 是一种有效的选择性的葡萄糖酰胺合
EX-527 S-enantiomer
(Catalog# : 17011802, Cas# :
848193-68-0
)
EX-527 S-enantiomer是一种有效的选择性SIRT1抑制剂,IC50为123 nM;没有对
EX-527 R-enantiomer
(Catalog# : 17011801, Cas# :
848193-69-1
)
EX-527 R-enantiomer是对活性形式EX-527 S-enantiomer(推测为参考)的负控制
4E1RCat
(Catalog# : 17011301, Cas# :
328998-25-0
)
4E1RCat是eIF4F翻译起始复合物的一种抑制剂,它阻止eIF4E:eIF4G和eIF4E
Etomoxir钠盐
(Catalog# : 17011103, Cas# :
828934-41-4
)
Etomoxir是一种在线粒体内膜的外表面的一种不可逆转的CPT-1抑制剂
Eganelisib ( IPI-549 )
(Catalog# : 711401, Cas# :
1693758-51-8
)
Eganelisib (IPI-549) 是一种首创、口服、高选择性 PI3Kγ 抑制剂,单独
Ezutromid
(Catalog# : 16122944, Cas# :
945531-77-1
)
Ezutromid, also known as BMN-195 and SMTC-1100, is a first orally bioavailable utroph
EXP-3174
(Catalog# : 16122943, Cas# :
124750-92-1
)
EXP-3174, also known as Losartan Carboxylic Acid, is a physiologically active metabol
Ertiprotafib
(Catalog# : 16122942, Cas# :
251303-04-5
)
Ertiprotafib, also known as PTP-112, is a Protein Tyrosine Phosphatase 1B Inhibitor (
Eptapirone
(Catalog# : 16122941, Cas# :
179756-85-5
)
Eptapirone, also known as F11440, is a potent, selective, high efficacy 5-HT1A recept
Eprodisate Sodium
(Catalog# : 16122940, Cas# :
36589-58-9
)
Eprodisate, also known as 3-PDS; NC-503; 3PDS, is an orally available disodium salt f
Emeramide ( BDTH2 )
(Catalog# : 16122939, Cas# :
351994-94-0
)
Emeramide, also known as BDTH2, is a mercury and heavy metal chelator. BDTH2 molecule
EMD534085
(Catalog# : 16122938, Cas# :
858668-07-2
)
EMD534085 is a kinesin inhibitor currently in clinical development.
Ellipticine
(Catalog# : 16122811, Cas# :
519-23-3
)
Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. Ellipt
Elacestrant dihydrochloride
(Catalog# : 16122810, Cas# :
1349723-93-8
)
Elacestrant dihydrochloride, also known as RAD1901, is an orally available, selective
Etravirine (TMC125)
(Catalog# : 16122767, Cas# :
269055-15-4
)
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used
Efavirenz
(Catalog# : 16122763, Cas# :
154598-52-4
)
Efavirenz is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with ant
Epoxomicin
(Catalog# : 16122762, Cas# :
134381-21-8
)
Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhib
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
Zongertinib ( BI 1810631 )
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).