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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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定制合成
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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定制合成
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订购信息
联系我们
公司简介
联系我们
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Cas号索引 2
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Cas号索引 2
2375815-63-5 | LY-3475070
(Catalog# : 21244)
LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alo
2097938-59-3 | Lerociclib HCl (G1T38 HCl)
(Catalog# : 2073106)
Lerociclib HCl (G1T38 dihydrochloride)是一种分化型口服CDK4 / 6抑制剂,对
2055050-87-6 | LAU159
(Catalog# : 2071505)
LAU159 is a potent modulator of α6β3γ2 GABAA receptor.
294623-49-7 | L006235
(Catalog# : 2061307)
L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays
2274819-46-2 | LUT-014
(Catalog# : 2042701)
LUT-014 is a B-Raf Inhibitor. Leveraging the paradoxical effect of B-Raf Inhibitors,
2135600-76-7 | LSZ102
(Catalog# : 2041502)
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50
2173037-97-1 | LY2794193
(Catalog# : 193262)
LY2794193是一种高效选择性的mGlu3受体激动剂。
2166616-75-5 | LY-3381916
(Catalog# : 193123)
LY-3381916是一种强效的、选择性的、脑透性的IDO1活性抑制剂,与缺
245075-84-7 | LR-90
(Catalog# : 19364)
LR-90是一种晚期糖基化终产物(AGE)抑制剂,可抑制人单核细胞的炎
2222755-14-6 | LOXO-292
(Catalog# : 192195)
LOXO-292 (ARRY-192)是一种口服和临床开发的选择性研究药物,用于治
292632-98-5 | L685458
(Catalog# : 186156)
L685458是一个强有力的和选择性γ分泌酶抑制剂。
2097002-61-2 | LOXO-195
(Catalog# : 185212)
LOXO-195是一种有效的选择性TRK抑制剂,能够解决在接受larotrectinib
2088939-99-3 | LYN-1604
(Catalog# : 18493)
LYN-1604是一种新型的ULK1激活剂,诱导细胞死亡,参与ATF3、RAD21和c
226929-39-1 | LB42708
(Catalog# : 18443)
LB42708是一种有效的、口服活性和选择性的非肽基转移酶抑制剂(FT
2040291-27-6 | LLY-283
(Catalog# : 184314)
LLY-283是一种有效、选择的针对PRMT5的SAM-竞争性化学探针。
231277-92-2 | 拉帕替尼
(Catalog# : 17022807)
拉帕替尼(GW-572016) 是一种有效的EGFR和ErbB2抑制剂,IC50分别为10.8和
27262-47-1 | Levobupivacaine free base
(Catalog# : 16123031)
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is
253863-00-2 | L-778123 hydrochloride
(Catalog# : 121805)
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and
248281-84-7 | Laquinimod
(Catalog# : 121506)
Laquinimod is an experimental immunomodulator developed by Active Biotech and Teva.
244240-24-2 | LFM-A13
(Catalog# : 52206)
Selective Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 M). Also inhibits poli
2630904-45-7 | MRTX1719
(Catalog# : 262401)
MRTX1719 is a potent and selective binder to the PRMT5•MTA complex and selectively
2448172-22-1 | (R)-4-((3-丙烯酰胺基哌啶-1-基)甲基)-N-(4-(4-吗啉-7H-吡咯并[2,3-D]嘧啶-6-基)苯基)吡啶-2-甲酰胺
(Catalog# : 20637)
2326521-71-3 | MRTX849
(Catalog# : 20611)
Adagrasib, also known as MRTX849, is a potent, highly selective, oral available KRAS
2377352-49-1 | Migoprotafib
(Catalog# : 20592)
Migoprotafib, also known as GDC-1971 and RLY-1971, is a SHP2 allosteric inhibitor. GD
2861190-30-7 | Mtb-IN-2
(Catalog# : 20572)
Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis
2565656-70-2 | muvalaplin
(Catalog# : 20528)
2747162-85-0 | MCUF-651
(Catalog# : 20470)
MCUF-651 is a small molecule guanylyl cyclase A receptor positive allosteric modulato
2654743-22-1 | MRTX0902
(Catalog# : 171462)
MRTX0902 是一种口服有效的 SOS1 的抑制剂,IC50 为 46 nM。
210113-85-2 | 4-(2-氨基乙氧基)苯甲酸甲酯盐酸盐
(Catalog# : 20407)
235748-94-4 | methyl (3-chloropyrazin-2-yl)acetate
(Catalog# : 20395)
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
2728667-27-2 | Zongertinib ( BI 1810631 )
(Catalog# : 24011)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).