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YL-109

Catalog No.: 110219
Cas No.: 36341-25-0
Purity : 98% 
110219 - YL-109 | CAS 36341-25-0

Catalog number : 110219

CAS number : 36341-25-0

Molecular Formula : C14H11NO2S 

Molecular Weight : 257.31 

Iupac Chemical Name : InChI=1S/C14H11NO2S/c1-17-12-8-9(6-7-11(12)16)14-15-10-4-2-3-5-13(10)18-14/h2-8,15H,1H3

Smile : COC1=CC(C2=NC3=CC=CC=C3S2)=CC=C1O

InChiKey : KRVBOHJNAFQFPW-UHFFFAOYSA-N

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SynonymsYP109; YP 109 
Molecular FormulaC14H11NO2S 
Molecular Weight257.31 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCOC1=CC(C2=NC3=CC=CC=C3S2)=CC=C1O
InChiKeyKRVBOHJNAFQFPW-UHFFFAOYSA-N
InChiInChI=1S/C14H11NO2S/c1-17-12-8-9(6-7-11(12)16)14-15-10-4-2-3-5-13(10)18-14/h2-8,16H,1H3
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YL-109 has ability to inhibit breast cancer cell growth and invasiveness in vitro and in vivo, which repressed the sphere-forming ability and the expression of stem cell markers in MDA-MB-231 mammosphere cultures. YL-109 increased the expression of carboxyl terminus of Hsp70-interacting protein (CHIP), which suppresses tumorigenic and metastatic potential of breast cancer cells by inhibiting the oncogenic pathway. 

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