+86-27-65522453 sales@sun-shinechem.com

Lapatinib

Catalog No.: 17022807
Cas No.: 231277-92-2
Purity : 98% 
17022807 - Lapatinib | CAS 231277-92-2

Catalog number : 17022807

CAS number : 231277-92-2

Molecular Formula : C₂₉H₂₆ClFN₄O₄S 

Molecular Weight : 581.06 

Iupac Chemical Name : Lapatinib 

Smile : CS(=O)(=O)CCNCc1ccc(o1)c2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5cccc(c5)F

InChiKey : BCFGMOOMADDAQU-UHFFFAOYSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsGW572016; GW-572016; GW 572016 
Molecular FormulaC₂₉H₂₆ClFN₄O₄S 
Molecular Weight581.06 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCS(=O)(=O)CCNCc1ccc(o1)c2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5cccc(c5)F
InChiKeyBCFGMOOMADDAQU-UHFFFAOYSA-N
InChiInChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
MDLMFCD09264194
Coming soon.

Lapatinib(GW-572016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

Lapatinib ditosylate is a selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases. ErbB-2 and EGFR dual tyrosine kinases are growth promoting factors that are over expressed in some breast cancer cell lines. Research studies have reported that Lapatinib Ditosylate can inhibit breast cancer cell proliferation.

 

231277-92-2 - Request Bulk Quote

×
231277-92-2 - Request Bulk Quote
Change