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MAPK
Membrane Transporter/Ion Channel
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Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
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Cas Index 4
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Cas Index 4
403811-55-2 | 10058-F4
(Catalog# : 102618)
10058-F4 is a cell-permeable thiazolidinone that specificallly inhibits the c-Myc-Max
458-45-7 | 3-(3-Fluorophenyl)Propionic Acid
(Catalog# : 90610)
Coming soon!
405911-17-3 | GW-3965 HCl
(Catalog# : 192251)
GW-3965 is a liver X receptor agonist. GW3965 represses the production of pro-inflamm
460330-27-2 | GT 949
(Catalog# : 187182)
GT 949 is a selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances
413611-93-5 | 10074-G5
(Catalog# : 1791112)
10074-G5 is a c-Myc/Max interaction inhibitor. 10074-G5, similarly to 10058-F4 (#F368
497833-27-9 | Givinostat
(Catalog# : 123008)
Givinostat is an orally bioavailable hydroxymate inhibitor of histone deacetylase (HD
439288-66-1 | GW 627368
(Catalog# : 91003)
GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with
452342-67-5 | GW788388
(Catalog# : 52305)
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibit
491833-30-8 | Genz-123346
(Catalog# : S1419)
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of c
412003-95-3 | 5-hydroxy-2,4-dimethylpyrimidine
(Catalog# : 2091204)
2,4-dimethylpyrimidin-5-ol is a key intermidiate ofLemborexant. Kg scale may be provi
422513-13-1 | Hesperadin
(Catalog# : 17011902)
Hesperadin is an inhibitor of human Aurora B, which can prevent the phosphorylation o
482-44-0 | Imperatorin
(Catalog# : 16123019)
Imperatorin, aslo known as Pentosalen, Marmelosin, is a furocoumarin and a phytochemi
467459-31-0 | Idalopirdine (Lu AE58054)
(Catalog# : 16122821)
Idalopirdine, also known as Lu AE58054 or Iladopirdine, is a potent and selective 5-H
448906-42-1 | IRAK-1-4 Inhibitor I
(Catalog# : 16062116)
IRAK-1-4 Inhibitor I
459789-99-2 | INT-747
(Catalog# : 122905)
INT-747 is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestati
461054-93-3 | Ko 143
(Catalog# : 111908)
Ko 143 is a potent and selective breast cancer resistance protein multidrug transport
4727-31-5 | Kartogenin
(Catalog# : 52215)
Kartogenin(KGN) is a small molecule stimulator of chondrogenesis; promotes chondrocyt
436133-68-5 | Kobe0065
(Catalog# : 52237)
Kobe0065 is a novel and effective small-molecule compound inhibiting RasCRaf interact
454453-49-7 | kobe2602
(Catalog# : 52401)
kobe2602 is a novel and effective small-molecule compound inhibiting RasCRaf interact
473921-12-9 | Lersivirine
(Catalog# : 25164)
Lersivirine, also known as UK-453061, is a novel second-generation non-nucleoside rev
47142-51-8 | LUN42518
(Catalog# : 2091908)
LUN42518, also known as Phentolamine Analogue 1, is an analogue of phentolamine. Phen
417716-92-8 | Lenvatinib (E7080)
(Catalog# : 52025)
Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascul
439239-90-4 | Lasmiditan
(Catalog# : 6111006)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor a
460331-61-7 | ML192
(Catalog# : 20464)
ML192, also known as MLS000526305 and CID1434953, is a selective ligands for GPR55. T
442898-34-2 | ML008
(Catalog# : 20112602)
ML008, also known as NCGC00092410, is a potent and selective inhibitor of glucocerebr
476476-54-7 | 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylic acid
(Catalog# : 2062320)
400755-41-1 | 3-methoxy-4-nitro-1H-pyrazole
(Catalog# : 5141901)
432001-69-9 | MDK-1699
(Catalog# : 184191)
MDK-1699, also known as Skp2 inhibitor C1 and SKPin C1, is a Skp2 inhibitor.
474645-27-7 | MMAE (Monomethyl auristatin E)
(Catalog# : 17022403)
MMAE, also known as Monomethyl auristatin E, is a synthetic antineoplastic agent. Bec
475085-57-5 | MRE-269
(Catalog# : 020106)
MRE-269 is a long-acting and highly selective prostacyclin receptor agonist.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
N/A | AF710B
(Catalog# : 25205)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
1235733-73-9 | (Rac)-AF710B
(Catalog# : 24083)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
863888-33-9 | Flurpiridaz-nonradiolabeled
(Catalog# : 25203)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
863888-32-8 | Flurpiridaz-Precursor
(Catalog# : 25202)
Flurpiridaz-Precursor in stock.
1800405-30-4 | KL1333
(Catalog# : 25201)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
1369489-71-3 | Palupiprant ( E7046 )
(Catalog# : 24055)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
2460722-04-5 | Oveporexton ( TAK-861 )
(Catalog# : 25194)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
2506273-81-8 | VT-3989
(Catalog# : 25200)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran