kobe2602 is a novel and effective small-molecule compound inhibiting RasCRaf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-RasGTP to c-Raf-1 RBD with a Ki value of 149 55 M.
For research use only. We do not sell to patients.
| Name | kobe2602 |
|---|---|
| Iupac Chemical Name | 2-(2,6-dinitro-4-(trifluoromethyl)phenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide |
| Synonyms | N/A |
| Molecular Formula | C14H9F4N5O4S |
| Molecular Weight | 419.31 |
| Smile | FC(C1=CC([N+]([O-])=O)=C(NNC(NC2=CC=C(F)C=C2)=S)C([N+]([O-])=O)=C1)(F)F |
| InChiKey | NNPBSITXCGPXJC-UHFFFAOYSA-N |
| InChi | InChI=1S/C14H9F4N5O4S/c15-8-1-3-9(4-2-8)19-13(28)21-20-12-10(22(24)25)5-7(14(16,17)18)6-11(12)23(26)27/h1-6,20H,(H2,19,21,28) |
| CAS Number | 454453-49-7 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |