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Enarodustat ( JTZ-951 )

Catalog No.: 2073104
Cas No.: 1262132-81-9
Purity : 98% Min.

Enarodustat ( JTZ-951 ) is an orally-active HIF-PH inhibitor with an EC50 of 0.22 Μm, that promotes erythropoiesis by accelerating the endogenous production of erythropoietin (EPO) and controlling the expression of molecules responsible for iron metabolism. The Phase 3 clinical studies confirmed efficacy in anemic patients with non-dialysis dependent CKD and dialysis dependent CKD. Furthermore, the favorable tolerability profile on safety of enarodustat was obtained during the studies

For research use only. We do not sell to patients.

Chemical Information

NameEnarodustat ( JTZ-951 )
Iupac Chemical NameN-[7-hydroxy-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl]glycine
Synonyms Enarodustat ; JTZ-951 ; JTZ 951 ; JTZ951 ;
Molecular FormulaC17H16N4O4
Molecular Weight340.33
SmileO=C(O)CNC(C1=C(O)C=C(CCC2=CC=CC=C2)N3C1=NC=N3)=O
InChiKeyNALAUGMPMIVAOW-UHFFFAOYSA-N
InChiInChI=1S/C17H16N4O4/c22-13-8-12(7-6-11-4-2-1-3-5-11)21-16(19-10-20-21)15(13)17(25)18-9-14(23)24/h1-5,8,10,22H,6-7,9H2,(H,18,25)(H,23,24)
CAS Number1262132-81-9
Related CAS1262132-81-9

Ordering Information

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Formulationcrystalline solid 
Purity98% Min.
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO, not in water
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

2073104 - Enarodustat ( JTZ-951 ) | CAS 1262132-81-9

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