| 编号 | 化学名称 | Cas号 | 纯度 | 化学结构 |
|---|---|---|---|---|
| 52109 | Trametinib (GSK1120212) | 871700-17-3 | 98% | ![]() |
| Trametinib (GSK1120212) is a highly specific and potentMEK1/2inhibitor withIC50of 0.9 | ||||
| 51614 | AMG-925 | 1401033-86-0 | 98% | ![]() |
| AMG-925 is a potent and orally bioavailable dual inhibitor of CDK4 and FLT3, includin | ||||
| 52026 | AMG-319 | 1608125-21-8 | 98% | ![]() |
| AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K tha | ||||
| 71805 | Capivasertib ( AZD5363 ) | 1143532-39-1 | 98% | ![]() |
| Capivasertib是一种新型的吡咯并嘧啶衍生物,是一种可口服的丝氨酸 | ||||
| 90731 | GDC-0810 ( Brilanestrant , ARN-810 ) | 1365888-06-7 | ≧98.0% | ![]() |
| GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader ( | ||||
| 92802 | SAG | 912545-86-9 | 99.03% | ![]() |
| SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopami | ||||
| 102703 | AZD-8835 | 1620576-64-8 | ≧98.0% | ![]() |
| AZD8835 is a potent and selective inhibitor ofPI3KαandPI3KδwithIC50s of 6.2 and 5.7 | ||||
| 111013 | MGCD-265-analog | 875337-44-3 | ≧98.0% | ![]() |
| MGCD-265-analogis a tyrosine kinase inhibitor that selectively targets MET and Axl.MG | ||||
| 112101 | AV-412 | 451492-95-8 | 99.38% | ![]() |
| AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth fact | ||||
| 120103 | AGI-5198 | 1355326-35-0 | 98% | ![]() |
| AGI-5198 is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen | ||||
| 122203 | Dalcetrapib | 211513-37-0 | 98% | ![]() |
| Dalcetrapib is a rhCETP inhibitor with IC50 of 0.2 M that increases the plasma HDL ch | ||||
| 122518 | SB-742457 ( Intepirdine ) | 607742-69-8 | 98% | ![]() |
| SB-742457(Intepirdine) is a highly selective 5-HT6 receptor antagonist with pKi of 9. | ||||
