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Ponatinib (AP24534)

Catalog No.: 52107
Cas No.: 943319-70-8
Purity : 98% 

Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFR, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively 

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Chemical Information

名称Ponatinib (AP24534)
Iupac 化学名称3-(2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide 
同义词N/A 
英文同义词N/A 
分子式C29H27F3N6O 
分子量532.56 
SmileN=1C=C(N2N=CC=CC21)C#CC=2C=C(C(=O)NC1=CC(=C(C=C1)CN1CCN(CC1)C)C(F)(F)F)C=CC2C
InChiKeyPHXJVRSECIGDHY-UHFFFAOYSA-N
InChiInChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)
Cas号943319-70-8
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Ordering Information

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纯度98% 
Handling
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Targets
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化学结构

52107 - Ponatinib (AP24534) | CAS 943319-70-8

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