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Baricitinib

Catalog No.: 51908
Cas No.: 1187594-09-7
Purity : 98% 
51908 - Baricitinib | CAS 1187594-09-7

Catalog number : 51908

CAS number : 1187594-09-7

分子式 : C16H17N7O2S 

分子量 : 371.42 

Iupac 化学名称 : 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]- 

Smile : C(C)S(=O)(=O)N1CC(C1)(CC#N)N1N=CC(=C1)C=1C2=C(N=CN1)NC=C2

InChiKey : XUZMWHLSFXCVMG-UHFFFAOYSA-N

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同义词Baricitinib;LY3009104;INCB028050 
英文同义词Baricitinib;LY3009104;INCB028050 
分子式C16H17N7O2S 
分子量371.42 
外观white solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature. 
SmileC(C)S(=O)(=O)N1CC(C1)(CC#N)N1N=CC(=C1)C=1C2=C(N=CN1)NC=C2
InChiKeyXUZMWHLSFXCVMG-UHFFFAOYSA-N
InChiInChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
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Baricitinib (also known as LY3009104 or INCB028050) is a novel and potent small molecule inhibitor of Janus kinase family of enzymes (JAKs) with selectivity for JAK1 and JAK2. Baricitinib is currently in clinical development for the treatment of rheumatoid arthritis (RA) and other inflammatory disorders.
Baricitinib is already in Phase III for RA and in Phase II for psoriasis and diabetic nephropathy.

 

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