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Apremilast(CC-10004)

Catalog No.: 51901
Cas No.: 608141-41-9
Purity : 98% 
51901 - Apremilast(CC-10004) | CAS 608141-41-9

Catalog number : 51901

CAS number : 608141-41-9

分子式 : C22H24N2O7S 

分子量 : 460.5 

Iupac 化学名称 : Acetamide, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- 

Smile : C(C)OC=1C=C(C=CC1OC)[C@@H](CS(=O)(=O)C)N1C(C2=CC=CC(=C2C1=O)NC(C)=O)=O

InChiKey : IMOZEMNVLZVGJZ-QGZVFWFLSA-N

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同义词Apremilast;CC-10004 
英文同义词Apremilast;CC-10004 
分子式C22H24N2O7S 
分子量460.5 
外观off-white solid 
纯度98% 
可溶性90mg/ml in DMSO 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
运输条件Shipped under ambient temperature. 
SmileC(C)OC=1C=C(C=CC1OC)[C@@H](CS(=O)(=O)C)N1C(C2=CC=CC(=C2C1=O)NC(C)=O)=O
InChiKeyIMOZEMNVLZVGJZ-QGZVFWFLSA-N
InChiInChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
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Apremilast (CC-10004) is a potent and orally active PDE4 and TNF- inhibitor with IC50 of 74 nM and 77 nM, respectively. 

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