LXH-3-71
Catalog No: 24107
CAS Number: 2251753-65-6
Purity: ≧97.0%
LXH-3-71 is novel "molecular glue" that induces the interaction between PHGDH and DDB1-CUL4 ubiquitin ligase, triggering degradation of PHGDH via the ubiquitination proteasome pathway and subsequently leading to inhibited cancer cell stemness.
仅供研究使用。 我们不向患者出售。
Chemical Information
| Name | LXH-3-71 |
|---|---|
| Iupac Chemical Name | (4aS,6aS,6bR,8aR,12aR,12bR,14bS)-N-(2-(3-(4-methoxyphenyl)ureido)ethyl)-2,2,6a,6b,9,9,12a-heptamethyl-11-methylene-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxamide |
| Synonyms | LXH-3-71 |
| 英文同义词 | LXH-3-71 |
| Molecular Formula | C41H59N3O4 |
| Molecular Weight | 657.94 |
| Smile | O=C([C@]1(CC[C@@]2(C)[C@]3(C)CC[C@@]4([H])C(C)(C)C5=O)CCC(C)(C)C[C@@]1([H])C2=CC[C@]3([H])[C@@]4(C)CC5=C)NCCNC(NC6=CC=C(OC)C=C6)=O |
| InChiKey | KHAFPBAKIVPZNQ-RRBGEOAMSA-N |
| InChi | InChI=1S/C41H59N3O4/c1-26-24-38(6)31(37(4,5)33(26)45)16-17-40(8)32(38)15-14-29-30-25-36(2,3)18-20-41(30,21-19-39(29,40)7)34(46)42-22-23-43-35(47)44-27-10-12-28(48-9)13-11-27/h10-14,30-32H,1,15-25H2,2-9H3,(H,42,46)(H2,43,44,47)/t30-,31-,32+,38-,39+,40+,41-/m0/s1 |
| CAS Number | 2251753-65-6 |
| 相关CAS号 | 2251753-65-6 |
Ordering Information
| 包装 | Price | 库存 | Purity | 备货期 |
|---|---|---|---|---|
| 大货 | Enquiry | Enquiry | Enquiry |
| 外观性状 | Off-white solid |
|---|---|
| Purity | ≧97.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| 处理方式 | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
