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Zibotentan

Catalog No.: 011908
Cas No.: 186497-07-4
Purity : 98% 
011908 - Zibotentan | CAS 186497-07-4

Catalog number : 011908

CAS number : 186497-07-4

分子式 : C19H16N6O4S 

分子量 : 424.433 

Iupac 化学名称 : N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide 

Smile : CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4

InChiKey : FJHHZXWJVIEFGJ-UHFFFAOYSA-N

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同义词ZD4054; ZD-4054 
英文同义词ZD4054; ZD-4054 
分子式C19H16N6O4S 
分子量424.433 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4
InChiKeyFJHHZXWJVIEFGJ-UHFFFAOYSA-N
InChiInChI=1S/C19H16N6O4S/c1-12-10-21-17(19(23-12)28-2)25-30(26,27)15-4-3-9-20-16(15)13-5-7-14(8-6-13)18-24-22-11-29-18/h3-11H,1-2H3,(H,21,25)
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Zibotentan is an orally available selective antagonist of the endothelin-A (ET-A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation. 

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