Zasocitinib is under development for the treatment of moderate to severe plaque psoriasis, psoriatic arthritis, inflammatory bowel disease (IBD) including crohn's disease (regional enteritis), ulcerative colitis and systemic lupus erythematosus. The drug candidate acts by targeting nonreceptor tyrosine protein kinase (TYK2).
仅供研究使用。 我们不向患者出售。
Name | Zasocitinib |
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Iupac Chemical Name | N-[(1R,2R)-2-Methoxycyclobutyl]-7-(methylamino)-5-[(2-oxo-2H-[1,2'-bipyridin]-3-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide |
Synonyms | Zasocitinib ; NDI-034858; TAK-279 ; |
英文同义词 | Zasocitinib ; NDI-034858; TAK-279 ; |
Molecular Formula | C23H24N8O3 |
Molecular Weight | 460.50 |
Smile | O=C(C1=C2N=C(NC3=CC=CN(C4=NC=CC=C4)C3=O)C=C(NC)N2N=C1)N[C@H]5[C@H](OC)CC5 |
InChiKey | BWINBHTTZLVXGT-NVXWUHKLSA-N |
InChi | InChI=1S/C23H24N8O3/c1-24-20-12-18(27-16-6-5-11-30(23(16)33)19-7-3-4-10-25-19)29-21-14(13-26-31(20)21)22(32)28-15-8-9-17(15)34-2/h3-7,10-13,15,17,24H,8-9H2,1-2H3,(H,27,29)(H,28,32)/t15-,17-/m1/s1 |
CAS Number | 2272904-53-5 |
相关CAS号 | 2272904-53-5 |
包装 | Price | 库存 | Purity | 备货期 |
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大货 | Enquiry | Enquiry | Enquiry |
外观性状 | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
处理方式 | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
海关编码 | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |