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ZSTK474

编号: 160926006
Cas号: 475110-96-4
纯度: 98% by HPLC 

Combination treatment using X-rays then ZSTK474 given orally for 8 days, starting 24h post-irradiation, significantly enhanced cell growth inhibition. The combined effect was also observed for clonogenic survival with continuous ZSTK474 treatment. Western blot analysis showed enhanced phosphorylation of Akt and GSK-3 by X-irradiation, whereas phosphorylation was inhibited by ZSTK474 treatment alone. Treatment with ZSTK474 after X-irradiation also inhibited phosphorylation, and remarkably inhibited xenograft tumor growth. 

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化学信息

名称ZSTK474
Iupac 化学名称4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine 
同义词ZSTK474; ZSTK-474; ZSTK 474 
英文同义词ZSTK474; ZSTK-474; ZSTK 474 
分子式C19H21F2N7O2 
分子量417.41255 
SmileFC(C1=NC2=C(N1C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1)C=CC=C2)F
InChiKeyHGVNLRPZOWWDKD-UHFFFAOYSA-N
InChiInChI=1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
Cas号475110-96-4
相关CAS号

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包装价格库存纯度备货期
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外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

160926006 - ZSTK474 | CAS 475110-96-4

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