ZLN005 is a PGC-1 Transcriptional Regulator, which shoed some beneficialfEffects on diabetic db/db mice. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice. Hyperglycemia and dyslipidemia also were ameliorated after treatment with ZLN005. Our results demonstrated that a novel small molecule selectively elevated the expression of PGC-1 in myotubes and skeletal muscle and exerted promising therapeutic effects for treating type 2 diabetes.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | ZLN005 |
| Iupac 化学名称 | ZLN005 |
| 同义词 | ZLN005; ZLN-005; ZLN 005 |
| 英文同义词 | ZLN005; ZLN-005; ZLN 005 |
| 分子式 | C17H18N2 |
| 分子量 | 250.33822 |
| InChiKey | |
| InChi | |
| Cas号 | 49671-76-3 |
| 相关CAS号 | |
| 外观性状 | crystalline solid |
| 纯度 | 98% |
| 存储 | 3 years -20ºCpowder |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |