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ZK-756326 dihydrochloride

Catalog No.: 16122850
Cas No.: 1780259-94-0
Purity : 98% 

ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM. ZK 756326 was a full agonist of CCR8, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1. 

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Chemical Information

名称ZK-756326 dihydrochloride
Iupac 化学名称ZK-756326 dihydrochloride 
同义词ZK-756326; ZK 756326; ZK756326; ZK-756326 dihydrochloride 
英文同义词ZK-756326; ZK 756326; ZK756326; ZK-756326 dihydrochloride 
分子式C21H30Cl2N2O3 
分子量429.382 
InChiKey
InChi
Cas号1780259-94-0
Related CAS

Ordering Information

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Formulationcrystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature as non-hazardous chemical. 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122850 - ZK-756326 dihydrochloride | CAS 1780259-94-0

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