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Y27632(free base)

Catalog No.: 16070918
Cas No.: 146986-50-7
Purity : 98% by HPLC 
16070918 - Y27632(free base) | CAS 146986-50-7

Catalog number : 16070918

CAS number : 146986-50-7

分子式 : C14H21N3O 

分子量 : 247.34 

Iupac 化学名称 : (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide 

Smile : C[C@H]([C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2)N

InChiKey : IYOZTVGMEWJPKR-IJLUTSLNSA-N

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同义词Y27632; Y-27632 
英文同义词Y27632; Y-27632 
分子式C14H21N3O 
分子量247.34 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC[C@H]([C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2)N
InChiKeyIYOZTVGMEWJPKR-IJLUTSLNSA-N
InChiInChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1
MDLMFCD03093855
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Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepatic fibrosis in rats, increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium, affects initial heart myofibrillogenesis in cultured chick blastoderm, promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord. 

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