Y-29794 Tosylate
编号: 16122848
Cas号: 129184-48-1
纯度: 98%
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. Y-29794 selectively and competitively inhibited rat brain PPCE (Ki = 0.95 nM) in a reversible manner. Ex vivo study demonstrated that Y-29794 could penetrate into brain to exhibit dose-dependent and long-lasting inhibition. Furthermore, Y-29794 could potentiate the effect of TRH on the release of ACh in the rat hippocampus. Y-29794 prevents the progression of A beta-like deposition in the hippocampus of the SAM.
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化学信息
| 名称 | Y-29794 Tosylate |
|---|---|
| Iupac 化学名称 | Y-29794 Tosylate |
| 同义词 | Y 29794; Y-29794; Y29794; Y29794 tosylate; Y-29794 tosylate; Y 29794 tosylate |
| 英文同义词 | Y 29794; Y-29794; Y29794; Y29794 tosylate; Y-29794 tosylate; Y 29794 tosylate |
| 分子式 | C30H42N2O4S3 |
| 分子量 | 590.86 |
| Smile | CC(C)c1ccc(c(n1)SCCCCCCCCN(C)C)C(=O)c2cccs2.C(=O)(C(=O)O)O |
| InChiKey | UUSSHPPSOUAHHP-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H34N2OS2.C2H2O4/c1-18(2)20-14-13-19(22(26)21-12-11-17-27-21)23(24-20)28-16-10-8-6-5-7-9-15-25(3)4;3-1(4)2(5)6/h11-14,17-18H,5-10,15-16H2,1-4H3;(H,3,4)(H,5,6) |
| Cas号 | 129184-48-1 |
| MDL | MFCD06411588 |
| 相关CAS号 |
订购信息
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