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XL647

Catalog No.: 111301
Cas No.: 781613-23-8
Purity : 98% 
111301 - XL647 | CAS 781613-23-8

Catalog number : 111301

CAS number : 781613-23-8

分子式 : C24H25Cl2FN4O2 

分子量 : 491.39 

Iupac 化学名称 : 7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine 

Smile : CN1CC2CC(CC2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC

InChiKey : HVXKQKFEHMGHSL-UHFFFAOYSA-N

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同义词XL-647; Tesevatinib; EXEL-7647; KD-019 
英文同义词XL-647; Tesevatinib; EXEL-7647; KD-019 
分子式C24H25Cl2FN4O2 
分子量491.39 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1CC2CC(CC2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC
InChiKeyHVXKQKFEHMGHSL-UHFFFAOYSA-N
InChiInChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)
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XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity; inhibits EGFR, HER2, VEGFR and EphB4 kinase. 

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