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XAV-939

Catalog No.: 52632
Cas No.: 284028-89-3
Purity : 98% 
52632 - XAV-939 | CAS 284028-89-3

Catalog number : 52632

CAS number : 284028-89-3

分子式 : C14H11F3N2OS 

分子量 : 312.31 

化学名称 : XAV-939

Smile : c1cc(ccc1c2nc3c(c(n2)O)CSCC3)C(F)(F)F

InChiKey : KLGQSVMIPOVQAX-UHFFFAOYSA-N

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分子式C14H11F3N2OS 
分子量312.31 
纯度98% 
Smilec1cc(ccc1c2nc3c(c(n2)O)CSCC3)C(F)(F)F
InChiKeyKLGQSVMIPOVQAX-UHFFFAOYSA-N
InChiInChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
MDLMFCD00106866
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XAV939 is a small molecule and selective Wnt pathway -catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively. 

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